Two-dimensional and three-dimensional cell culture models in vitro: pros and cons
نویسندگان
چکیده
منابع مشابه
infinite dimensional garch models
مدلهای گارچ در فضاهای هیلبرت پایان نامه حاضر شامل دو بخش می باشد. در قسمت اول مدلهای اتورگرسیو تعمیم یافته مشروط به ناهمگنی واریانس در فضاهای هیلبرت را معرفی، مفاهیم ریاضی مورد نیاز در تحلیل این مدلها در دامنه زمان را مطرح کرده و آنها را مورد بررسی قرار می دهیم. بر اساس پیشرفتهایی که اخیرا در زمینه تئوری داده های تابعی و آماره های عملگری ایجاد شده است، فرآیندهایی که دارای مقادیر در فضاهای ...
15 صفحه اولthree-dimensional (3d) cell culture conditions, present and future improvements
conclusions our underlying hypothesis is that recapitulating the three-dimensional early embryonic structure, in order to reproduce better in vitro the three-dimensional morphogenetic-like re-arrangements, would improve cells differentiation, when in vivo transplanted; moreover, it could be used as a simplified cancer disease model and reliable drug evaluation method as well. results the proces...
متن کاملThree-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning
Drug development is a lengthy and costly process that proceeds through several stages from target identification to lead discovery and optimization, preclinical validation and clinical trials culminating in approval for clinical use. An important step in this process is high-throughput screening (HTS) of small compound libraries for lead identification. Currently, the majority of cell-based HTS...
متن کاملPossibility and Reproducibility of Renal Assessing and Size Measurement by Three- Dimensional vs Two- Dimensional Ultrasounographv in Dogs
Objective- To determine the possibility and reproducibility of three-dimensional ultrasonography (3DUS)and comparison of the achieved measurements to normal two-dimensional ultrasonography (2DCS)Design- Descriptive studyAnimals- 10 young mixed normal dogs, age 1.5-2.5 year, weighing 9.7-12 kg Procedure- Renal width, length, and depth measured in coron al and transverse sections. The measurement...
متن کاملBioSig3D: High Content Screening of Three-Dimensional Cell Culture Models.
BioSig3D is a computational platform for high-content screening of three-dimensional (3D) cell culture models that are imaged in full 3D volume. It provides an end-to-end solution for designing high content screening assays, based on colony organization that is derived from segmentation of nuclei in each colony. BioSig3D also enables visualization of raw and processed 3D volumetric data for qua...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bulletin of Siberian Medicine
سال: 2018
ISSN: 1819-3684,1682-0363
DOI: 10.20538/1682-0363-2018-3-188-196